answers to cancer that matter
We are rewinding cancer’s trajectory back to the beginning. We have identified biological programs that are present in the earliest forms of cancer, before the development of tumors, before the onset of symptoms, before the cancer becomes a problem. Biological programs that link oncogenesis and developmental biology.
Up until now, the approach to early cancer detection has been to try to reverse engineer cancer – looking back from late-stage disease to see if the same genetic biomarkers are present in the very earliest tumors. However, while this approach is a significant advancement from decades ago, this conventional view of tumor development, a genetically divergent disease, relies on moving targets that are reflective of late-stage cancers.
It turns out that most cancers converge on one common epigenetic-based biological program.
Harbinger’s approach is rooted in this fundamental insight. We have identified biological programs derived from developmental biology that are present in the earliest cellular changes of cancer and are shared across most cancers – biological programs that signal the initiation of oncogenesis. We see cancer at the beginning, even before it takes hold.
Our biological insights tell us ‘where to look’, maximizing the signal to detect cancer before it develops. Using biology guided machine learning approaches, we can accurately predict where and how cancer will grow and provide clues to help inform when and where to treat it. This puts fear to rest. This is the answer before cancer becomes a problem.
